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+--- Thread: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. (/showthread.php?tid=22515)
Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - Wao nahele kane - 12-02-2021
Due to our nationally higher exposure rate to harmful UV radiation in Hawaii, we experience a much higher rate of skin cancers. So much so, it's not considered as dire a diagnosis in Hawaii vs. other states across the USA. It's just a common thing out here.
Our dog developed basal cell carcinoma a little over a year ago. The vet wanted to schedule him for surgery that consisted of him going under anesthesia. Our dog doesn't like anesthesia. He will tremble substantially if we revisit a vet that has put him under with anesthesia. Not sure why that is, maybe he's the type that can still feel all the pain and remember everything when under. For whatever the reason, we have a moral obligation to avoid anesthesia for him, if possible.
After his original diagnosis we debated on how to approach the surgery, our biggest concern was the anesthesia aspect. Long story short, he developed large bulbous scab that prompted us to see the vet to begin with and those bulbous scabs would on occasion seperate from the lesion and bleed a while. Typically we used Neosporin on the lesion to stave off infection till it scabbed back over. After a few months of this and the lesion was growing larger, we were out of Neosporin after an incident his scab seperated. We happened to have a tube of Mupirocin on hand and decided to use it instead, just a human prescription based antibiotic, also safe for dogs.
After a couple weeks use of Mupirocin, the legion shrunk down to 1/10th of the size it had grown to with no bulbous scab developing. We gave it week rest period of use and the legion remained lightly (normal) scabbed over but didn't produce the bulbous scab and didn't get any larger. Then we continued with another couple weeks use, this time the entire legion healed up and the raised mole it was on, shrunk up to around half of its amassed size. Gave it another weeks rest and applied it for another couple weeks and the mole had all but vanished, leaving a wrinkled skin behind from being stretched out by the giant mole it had ammased to. The reason for the rest periods between application periods is to avoid possible fungal infection.
This wasn't something that was supposed to happen, not with a topical antibiotic. It shouldn't have healed and it had been this way for months, not healing, only getting larger. I decided to look up Mupirocin use with skin cancers and found it had been recently spit out of a drug repurposing computer program as possibly being effective against cancers. They ran preliminary tests and found it indeed was effective against skin cancer and study suggested further indepth testing was warranted.
So, now our dog is at a stage where he can get a local anesthetic for a minor skin surgery of a current benign stage basal cell, instead of the condition he was in, before inadvertently fighting the cancer back.
As anecdotal as the above is, still felt it worth sharing for people who might be diagnosed with skin cancer, you might mention Mupirocin to your doctor, cite the below study and see what they think about using it as an interim treatment while waiting to get a surgery scheduled. It may prove very beneficial.
These are the photos of the lesion without the bulbous scab on it, before being inadvertently battled by Mupirocin. The last photo is after Mupirocin treatment.
[attachment=63]
https://www.future-science.com/doi/10.4155/fmc-2018-0333#:~:text=Mupirocin%20showed%20low%20toxicity%20against,in%20mupirocin%2Dtreated%20cancer%20cells.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - 'elepaio - 12-02-2021
Shoots, this is awesome. THANK YOU to share this.
Have a couple tubes here of it languishing.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - kimo wires - 12-02-2021
OOps. I hadn't entered anything in the field when i hit post too soon so I deleted it.
I have eradicated several BCCs over the years with homemade CO. It would probably work for dogs too.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - Wao nahele kane - 12-03-2021
Update:
After today's jaw dropping vet appointment.
Vet says no need for surgery now and sent him home with backup prescription of Mupirocin should it become problematic again.
Vet stoked to see this and excited to begin using the treatment method for other pets as "these are rather tricky" cancers to deal with.
Should it provide similar results for other pets, we'll have a valuable non-invasive tool to battle the issue.
(12-02-2021, 07:10 AM)kimo wires Wrote: OOps. I hadn't entered anything in the field when i hit post too soon so I deleted it.
I have eradicated several BCCs over the years with homemade CO. It would probably work for dogs too.
If you can provide small tissue samples of the affected tissue, with and without treatment to a local lab for efficacy and you get a positive observation. You can move it forward through the chain of the study process. Spendy process though, unless, you turn those results over to a university who's willing to run with it or take a chance with a pharmaceutical Co or a smaller R&D lab.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - malahini - 12-03-2021
Which vet was it btw?
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - 'elepaio - 12-03-2021
Mr.Wao,
Did you keep it covered ? Like light gauze wrap or ?
mahalo for posting this positive news.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - AaronM - 12-03-2021
Hooray!
Your pooch is blessed to have you. And naturally, vice-versa.
Agree with 'elepaio, good news is good news!
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - Wao nahele wahine - 12-03-2021
It was the Aloha Veterinary Center in Hilo. No gauze wrap or covering needed after application of mupirocin.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - 'elepaio - 12-03-2021
Ok ok.gonna try. Who knew ???
Thank you again.
RE: Basal Cell Carcinoma (Skin cancer) potential additional treatment to come. - Wao nahele kane - 12-04-2021
(12-02-2021, 07:10 AM)kimo wires Wrote: OOps. I hadn't entered anything in the field when i hit post too soon so I deleted it.Meant to ask, is it composed of polyphenolics from peach extracts or some other commonly accessible extract?
I have eradicated several BCCs over the years with homemade CO. It would probably work for dogs too.