12-21-2020, 12:23 AM
Antibody dependent enhancement is the term for what happened with the Dengue fever
vaccine. It made infections MORE severe rather than less. Worst case scenario!
Well, if that is to happen with coronavirus, and research at this time suggests highly unlikely,
then poor old folks and front line health care workers dropping off with serious disease will
soon follow.
This is an interesting comparison of flu and Covid that recently came to my attention.
“For those who many months later insist on comparing covid to the flu here is a new Lancet study. It focused on hospitalized patients but still captures key differences between the diseases. The conclusion: "The presentation of patients with COVID-19 and seasonal influenza requiring hospitalisation differs considerably".
Disease process: "Patients admitted to hospital with COVID-19 more frequently developed acute respiratory failure, pulmonary embolism, septic shock, or haemorrhagic stroke than patients with influenza, but less frequently developed myocardial infarction or atrial fibrillation."
Patient characteristics: "Patients with COVID-19 were more frequently obese or overweight, and more frequently had diabetes, hypertension, and dyslipidaemia than patients with influenza, whereas those with influenza more frequently had heart failure, chronic respiratory disease, cirrhosis, and deficiency anaemia."
https://www.thelancet.com/journals/l...527-0/fulltext
This study while new examined patients hospitalized last spring. In the intervening months, there only appears to be increasing evidence that covid can be much more unpredictable in younger patients than influenzas.
The cohort for potentially severe risk of covid disease is broader than that for influenza. We've seen that in practice but again note the patient characteristics in the Lancet study.
While those who die from covid continue to be elderly, the median age of those who become ill and hospitalized is younger. With that increasingly evident during the summer and fall as covid moved from the nursing homes into the general population. Needless to say that comes with all sorts of economic consequences. Like what we've seen for the last several months.“
vaccine. It made infections MORE severe rather than less. Worst case scenario!
Well, if that is to happen with coronavirus, and research at this time suggests highly unlikely,
then poor old folks and front line health care workers dropping off with serious disease will
soon follow.
This is an interesting comparison of flu and Covid that recently came to my attention.
“For those who many months later insist on comparing covid to the flu here is a new Lancet study. It focused on hospitalized patients but still captures key differences between the diseases. The conclusion: "The presentation of patients with COVID-19 and seasonal influenza requiring hospitalisation differs considerably".
Disease process: "Patients admitted to hospital with COVID-19 more frequently developed acute respiratory failure, pulmonary embolism, septic shock, or haemorrhagic stroke than patients with influenza, but less frequently developed myocardial infarction or atrial fibrillation."
Patient characteristics: "Patients with COVID-19 were more frequently obese or overweight, and more frequently had diabetes, hypertension, and dyslipidaemia than patients with influenza, whereas those with influenza more frequently had heart failure, chronic respiratory disease, cirrhosis, and deficiency anaemia."
https://www.thelancet.com/journals/l...527-0/fulltext
This study while new examined patients hospitalized last spring. In the intervening months, there only appears to be increasing evidence that covid can be much more unpredictable in younger patients than influenzas.
The cohort for potentially severe risk of covid disease is broader than that for influenza. We've seen that in practice but again note the patient characteristics in the Lancet study.
While those who die from covid continue to be elderly, the median age of those who become ill and hospitalized is younger. With that increasingly evident during the summer and fall as covid moved from the nursing homes into the general population. Needless to say that comes with all sorts of economic consequences. Like what we've seen for the last several months.“